منابع مشابه
Current status of lupus nephritis
Systemic lupus erythematosus (SLE) is a systemic disease of unknown aetiology with variable course and prognosis. Lupus nephritis (LN) is one of the important disease manifestations of SLE with considerable influence on patient outcomes. Immunosuppression therapy has made it possible to control the disease with improved life expectancy and quality of life. In the last few decades, various studi...
متن کاملThe prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
متن کاملTreatment of severe proliferative lupus nephritis: the current state.
Despite the development of new modalities, cyclophosphamide (CYC) remains the preferred initial treatment for severe proliferative lupus nephritis. Controversies continue about the best route, dosage, and duration of CYC treatment. For recalcitrant disease, new immunosuppressive and immunomodulating agents, immunoablative high dose CYC, nucleoside analogues, apheresis, and the biological respon...
متن کاملCurrent therapy of lupus nephritis. Which is the best option?
Renal involvement in systemic lupus erythematosus (SLE) is an important cause of morbidity and mortality, reaching a prevalence of 39% during the course of the disease. Currently, the therapy for severe lupus nephritis is based on the use of high-dose corticosteroids and immunosuppressive drugs, being traditionally cyclophosphamide the most frequently used agent. Recent studies have demonstrate...
متن کاملHidden face of lupus nephritis exposed: Isolated tubulointerstitial lupus nephritis.
Implication for health policy/practice/research/medical education: Systemic lupus erythematosus (SLE) is a common multisystemic immunological disorder with protean manifestations. It commonly involves the kidney, which is associated with significant morbidity and mortality. In the kidney, it typically affects glomeruli and blood vessels with secondary involvement of tubulointer-stitial componen...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2003
ISSN: 0003-4967
DOI: 10.1136/ard.62.9.795